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DNA Fragmentation / FISH Fragmentation

he DNA fragmentation test is a test developed around 2000 in America and measures the proportion of healthy spermatozoa in relation to those that have altered DNA inside them.

A sperm with fragmented DNA will lead to a pregnancy that has high chances for miscarriage and if not, with a malformed fetus that cannot survive.

DNA fragmentation test is mainly used as a predictor and can sometimes justify unexplained infertility or predict a poor assisted reproductive outcome.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643675/